Investor Relations

Advaxis and Vibalogics to Co-Develop Stable Storage Formulation for Live Vaccines

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Marketing Potential Across Global Biologics Industry

NORTH BRUNSWICK, N.J.-- Advaxis, Inc., (OTCBB: ADXS), the live, attenuated Listeria monocytogenes (Listeria) immunotherapy company and Vibalogics GmbH, a German biologics manufacturing company, have agreed to co-develop a room temperature stable, processing technology for live vaccines originally engineered for Advaxis.

Most live vaccines are stored via freeze drying called lyophilization. This drying method may not be suitable for all products, as it frequently kills most of the microorganism; depending upon the organism type and related recovery and stability issues. Based on Vibalogics' drying experience, a new method has been found that allows for a room temperature, storage-stable form of Advaxis' live Listeria vaccines with a very high recovery.

"This process, which we are currently developing for our Listeria immunotherapeutics, shows promise in its use with other living micro-organisms," commented Advaxis Chairman/CEO Thomas A. Moore. "Although it is intended for use with Listeria, other companies and academic institutions that use living microorganisms (e.g., Salmonella, E. coli) may benefit from this process. This initiative does not require significant development funds from Advaxis, vastly increases the commercial properties of our products, and can increase our short- and long-term shareholder value."

About Vibalogics, GmbH

Vibalogics is a partner for companies committed to developing therapeutic and prophylactic vaccines and biologics. The company is a single site for GMP-compliant manufacturing, formulating, filling and lyophilization of drugs based on recombinant or wild-type viruses and bacteria. The drugs are predominantly used for vaccinations, treatment of life-threatening diseases, virotherapy or gene therapy.

About Advaxis, Inc.

Advaxis is a biotechnology company developing proprietary, live, attenuated Listeria monocytogenes (Listeria) vaccines that deliver engineered tumor antigens, which stimulate multiple, simultaneous immunological mechanisms to fight cancer. Today, the Company has nine (9) distinct, cancer-fighting constructs in various stages of development, directly and through strategic collaborations with such recognized sites of excellence as the City of Hope, the Roswell Park Cancer Institute, the National Cancer Institute, the University of Pittsburgh and Cancer Research - UK. Advaxis' technology was developed by Dr. Yvonne Paterson, professor of microbiology at the University of Pennsylvania and chairperson of Advaxis' scientific advisory board.

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    Source: Advaxis, Inc.